Showing 2 results for Antibacterial Activity
N. Yazdani, J. Javadpour, B. Eftekhari Yekta, M. Hamrang,
Volume 16, Issue 1 (3-2019)
Abstract
This study focuses on the physical, magnetic, biological and antibacterial behaviour of cobalt-doped HAp powder samples. Pure and Cobalt- doped HAp nanoparticles were synthesized by hydrothermal method. Calcium nitrate, di- ammonium hydrogen phosphate and cobalt nitrate were used as precursor materials. The synthesized powders were characterized using x-ray diffraction pattern (XRD), fourier transform infrared spectroscopy (FTIR), field emission scanning electron microscopy (FESEM), vibrating sample magnetometer (VSM), Raman spectroscopy as well as MTT assay and cell adhesion test. Disc diffusion method was used to investigate antibacterial activity of the samples. The results confirmed the substitution of Ca by Co ions in the HAp lattice. In addition, this substitution induced size reduction and morphology change in HAp particles. All cobalt substituted HAp powder samples displayed paramagnetic properties, as opposed to the diamagnetic behaviour observed in the pure HAp samples. In addition, these nanoparticles exhibited cell adhesion, biocompatibility and antibacterial activity against S.aureus bacteria.
This study focuses on the physical, magnetic, biological and antibacterial behaviour of cobalt-doped HAp powder samples. Pure and Cobalt- doped HAp nanoparticles were synthesized by hydrothermal method. Calcium nitrate, di- ammonium hydrogen phosphate and cobalt nitrate were used as precursor materials. The synthesized powders were characterized using x-ray diffraction pattern (XRD), fourier transform infrared spectroscopy (FTIR), field emission scanning electron microscopy (FESEM), vibrating sample magnetometer (VSM), Raman spectroscopy as well as MTT assay and cell adhesion test. Disc diffusion method was used to investigate antibacterial activity of the samples. The results confirmed the substitution of Ca by Co ions in the HAp lattice. In addition, this substitution induced size reduction and morphology change in HAp particles. All cobalt substituted HAp powder samples displayed paramagnetic properties, as opposed to the diamagnetic behaviour observed in the pure HAp samples. In addition, these nanoparticles exhibited cell adhesion, biocompatibility and antibacterial activity against S.aureus bacteria.
Chimmachandiran Suresh Kumar, Kaliyan Dhanaraj, Ramasamy Mariappan Vimalathithan, Perumal Ilaiyaraja, Govindhasamy Suresh,
Volume 18, Issue 1 (3-2021)
Abstract
The Nano Hydroxyapatite (HAp), HAp/PEG and HAp/PVP powders derived from both Gastropod shell (natural source) and chemical precursor by the precipitation method were characterized through various characterization techniques such as FT-IR, XRD, SEM-EDX, TEM, Antibacterial activity and SBF analysis. Based on the structural, chemical, morphological and biological characteristics, HAp/PVP from natural and chemical precursors have been compared successfully. Calculated structural parameters, crystallinity index, C/P ratio, morphology, antibacterial activity and SBF analysis of the products show that HAp/PVP-S (derived from a natural source) exhibits good mechanical property, rod like morphology, good antibacterial activity and apatite formation ability at 14 days. EDX analysis also shows the presence of carbon and sodium in HAp/PVP-S. Comparative analysis reveals that characteristics of HAp/PVP-S such as high carbonate content, low crystallite size, poor crystalline nature, presence of trace metal, non-stoichiometric elemental composition and rod like crystals which are matched with the characteristics of biological apatite. Thus, the HAp/PVP-S has the ability to form bone apatite.
